The majority of compounded formulations used by dentists are for direct application to the oral cavity, usually in the forms of mouthwashes, or oral pastes or powders.

Mouthwashes

Mouthwashes may be compounded for a variety of disorders such as recurrent ulcerative stomatitis, local infections, periodontitis, and chemical burns, and may contain any of a number of drugs, alone or in combination. The choice of ingredients depends upon the cause and the severity of the condition.

 

When contact between a therapeutic preparation and lesion must be longer than that afforded by a mouthwash, a mucoadhesive powder or oral paste may be an appropriate dosage form.

Mucoadhesive Powders

Mucoadhesive powders usually contain a hydrophilic polymer, which hydrates in contact with water, and another component that confers adhesion to the mucosa. There are several formulations that can be used as the vehicle for a mucoadhesive powder.

Oral Powders

As an alternative to powders, an oral paste may be compounded for application inside the oral cavity. These pastes are usually anhydrous and hydrophobic in nature so saliva won’t “wash out” the medication once it is applied.

For more information on our range of compounded dental preparations, speak to one of our compounding pharmacists. At Priceline Pharmacy Pacific Fair, we are able to collaborate with your dentist, to prepare a customized dental solution for your individual needs.

 

References:

Fonseca, S. (2006). Basics of compounding for dentistry, part 1: Effective approaches and formulations. International Journal of Pharmaceutical Compounding, 10(2), 122-127.